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Data Availability Available from the corresponding author on reasonable request

J Neuroimmunol 284:5766 Carlton WW (1969) Spongiform encephalopathy induced in rats and guinea pigs by cuprizone

Abbreviations: ALT alanine transaminase CYP the cytochrome P450 INR international normalized ratio References [1] Kur P, Kolasa-Woosiuk A, Misiakiewicz-Has K, Wiszniewska B

Chronic inflammation and microvascular factors Another area of interest in tinnitus research involves chronic inflammation and microcirculatory disturbances, which may contribute to tissue stress and increased neural excitability